The Definitive Guide to ceesdekker
The Definitive Guide to ceesdekker
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Our group scientific studies bacterial cell division and is particularly aiming to represent a ‘bottom up biology’ in synthetic cells that may autonomously divide. Our main fascination lies in cell division, chromatin structure, and spatial Command.
Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
2007, very first genuine-time detection of strand Trade in homologous recombination by RecA; discovery of the low persistence size of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
We produce level-of-care diagnostics exam of neglected tropical health conditions within just source-limited configurations, determined by Crspr/Cas9 detecting of pathogen’s DNA in entire body fluids.
SMC complexes can go Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion
We use nanofabricated microfluidic structures to sample spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks which evaluate the fundamental job of spatial confinement with the molecular and cellular amount. Our assignments consist of the subsequent:
Illustration (one) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is demonstrated in grey, the rim in the pore is highlighted in crimson, as well as a 3D rendering in the motion with the DNA rod is shown.
In 1993, for a youthful and eager associate professor at Delft College of Technology, I had originally concentrated the research attempts of my team on measuring the electrical conductance of a single conducting-polymer molecule. Inside of two yrs, we experienced created a device during which one wire of the phthalocyaninepolysiloxane polymer was related in between two closely spaced steel nanoelectrodes.
But carbon nanotubes have remained a investigate subject matter of appreciable fascination to a lot of. Without a doubt, the outlook on making use of carbon nanotubes to create useful gadgets, in locations like radio-frequency electronics, electronic electronics and versatile electronics, stays vibrant.
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Several new phenomena were learned, and he and his analysis team proven a number one placement Within this industry of analysis. Dekker and his research group discovered new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the main to create a transistor based on an individual nanotube molecule.
For example, we think about the nucleopore complicated, a gateway between the mobile nucleus as well as the cytoplasm. This is a very sophisticated process and so difficult to analyze in the cell, so we use biomimetics. We reconstruct holes after which you can insert https://www.ceesdekker.net specific factors of the nucleopore advanced to review transportation by way of it at the single-molecule stage.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)